Ultrasound Guided Core Biopsy vs Fine Needle Aspiration for Evaluation of Axillary Lymphadenopathy in Patients Suspected of Having Breast Cancer.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 105
- 试验地点
- 2
- 主要终点
- Fraction of metastatic nodes found at axillary surgery that were identified pre-surgically by FNA vs. core biopsy
研究概览
简要总结
The study was performed to determine if either ultrasound guided core biopsy or fine needle aspiration of an axillary lymph node has superior sensitivity in detecting metastatic carcinoma from the ipsilateral breast.
详细描述
Women with suspected or recently diagnosed breast cancer and ipsilateral abnormal appearing axillary lymph nodes underwent fine needle aspiration immediately followed by core biopsy of the same lymph node.Cytology results from the fine needle aspiration (FNA)and histology from the core biopsy were compared to surgical pathology from axillary node excision to determine if either method of percutaneous node sampling was more sensitive in detecting metastasis. Pain during each procedure was also compared.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Women with breast cancer and abnormal ipsilateral axillary nodes visible on sonography.
排除标准
- •Inability to understand consent form.
- •Emotionally unprepared to discuss possibility of axillary metastasis
- •Node not amenable to core biopsy
结局指标
主要结局
Fraction of metastatic nodes found at axillary surgery that were identified pre-surgically by FNA vs. core biopsy
时间窗: 1 week to 10 months
Results of FNA cytology and core biopsy histology are compared to axillary surgery results.
次要结局
未报告次要终点
研究者
Marie Ganott
MD
University of Pittsburgh