Development and Research of an Individualized Intelligent Platform for Rehabilitaion in Patients With Parkinson's Disease
试验速览
- 阶段
- 不适用
- 入组人数
- 75
- 试验地点
- 1
- 主要终点
- mini-BESTest
研究概览
简要总结
The present study aims to compare the clinical efficacy of intelligent POWER therapy, intelligent LSVT-BIG therapy, and the three exercise models currently in clinical use. DCM_IR analysis will also be incorporated into the analysis to develop a personalized and intelligent Parkinson's rehabilitative therapy platform.
详细描述
Background:
Parkinson's disease is a progressively degenerative disorder. Patients need early screening, therapeutic intervention, and personalized interaction with outpatient rehabilitative treatment. In the past, it had been difficult to meet these goals. Recent advances in bio-sensors technology has enabled collection of bio-metric data. Models of brainwave analysis have also matured. In addition, our ability to analyze vibrational spectrogram had also greatly improved. How to combine these enabling technologies to meet the needs of Parkinson's patients is an urgent topic of research.
Objective:
The present study aims to compare the clinical efficacy of intelligent POWER therapy, intelligent LSVT-BIG therapy, and the three exercise models currently in clinical use. DCM_IR analysis will also be incorporated into the analysis to develop a personalized and intelligent Parkinson's rehabilitative therapy platform.
Method:
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 40 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •.Parkinson's disease diagnosis, Hoehn-Yahr level I-III
- •.Stable medicine intake for 2 weeks at least
- •.Able to walk independently for 15 meters
- •.Aged 40-85 years old
排除标准
- •.Cognition deficits(MMSE score<24)
- •.Combined other neurological disease, such as stork, SCI, and so on.
- •.Pregnant or Breastfeeding
研究组 & 干预措施
LSVT-BIG
Participants in this group would be treated with LSVT-BIG for three months
干预措施: LSVT-BIG (Other)
POWER
Participants in this group would be treated with POWER for three months
干预措施: POWER (Other)
Traditional rehabilitation
Participants in this group would be treated with traditional exercise rehabilitation for three months
干预措施: Traditional rehabilitation (Other)
结局指标
主要结局
mini-BESTest
时间窗: 15 mins
Mini BESTest assesses dynamic balance, a unidimensinal construct and includes 14 items addressing 4 of the 6 sections of the original BESTest (anticipatory postural adjustments, reactive postural control, sensory orientation, dynamic gait).
次要结局
- Unified Parkinson's disease rating scale(15 mins)
- muscle power of lower extremity(5 mins)
- PDQ-39(30 mins)