Gammaglobulins Level is Predictive Factor of Evolution in Sarcoidosis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 78
- 试验地点
- 1
- 主要终点
- Study of gamma globulin level present in the blood at the time of diagnosis of sarcoidosis on disease activity
研究概览
简要总结
Evaluation of the rate of achievement of serum protein electrophoresis (PPE) in diagnosis in a retrospective cohort of patients at Rennes University Hospital
详细描述
In 50% of cases, sarcoidosis is associated with polyclonal hypergammaglobulinemia. The other forms have a normal gamma globulin level.
The level of gamma globulinemia has not yet been studied as an evolutionary predictive factor. Furthermore, there are disseminated granulomatoses sharing common characteristics with sarcoidosis, associated with Common Variable Immunodeficiency deficit (DICV) type Primary Immunodeficiency syndrome (DIP), thus occurring in hypogammaglobulinemic patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients newly diagnosed with sarcoidosis
排除标准
- •Comorbidity responsible for a change in the level of gamma globulin
- •Other etiology of granulomatosis
结局指标
主要结局
Study of gamma globulin level present in the blood at the time of diagnosis of sarcoidosis on disease activity
时间窗: Day 1
Electrophoresis rates of serum proteins
Study of gamma globulin level present in the blood at the time of diagnosis of sarcoidosis on the course of the disease
时间窗: Day 1
Electrophoresis rates of serum proteins
次要结局
未报告次要终点