Coronary Artery Calcification Assessed on PET Scanner (PET : Positron Emission Tomography)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Prevalence of moderate calcification artery calcium (CAC) in participants without history of cardiac disease
研究概览
简要总结
Calcification artery calcium (CAC) scoring is a valuable tool for determining the risk of major adverse cardiac events.
It was found that CAC can be quantitatively assessed, by manual scoring or using deep-learning, on low-dose non electrocardiogram-gated, contrast-enhanced or non-enhanced computed tomography (CT-scan) performed in association of PET acquisition, with a good agreement with standard scans.
The purpose of this study is to determine the impact of a systematic coronary artery calcification evaluation in patients undergoing flourine-18 fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) imaging to improve primary prevention of cardiovascular diseases.
A visual calcification artery calcium assessment will be made for each patient, dividing them into four groups: none, mild, moderate or heavy calcification artery calcium. When possible, a calcification artery calcium score will be computed.
Each patient will complete a questionnaire to collect risk factors, history of cardiovascular diseases and medications.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients referred for a 18F-FDG PT/CT imaging
- •Patients aged 18 and older
排除标准
- •Patients who already participated in this study (in case of follow-up PET/CT scans)
- •Unusable CT scan due to CT artifacts or poor-quality images
- •Patients referred for a brain 18F-FDG PET/CT imaging
- •Protected adults
- •Pregnant or breastfeeding women
结局指标
主要结局
Prevalence of moderate calcification artery calcium (CAC) in participants without history of cardiac disease
时间窗: Baseline
In participants who had neither history of cardiac disease nor cardiology follow-up, the proportion of those with at least moderate CAC
次要结局
- Prevalence of coronary heart disease among participants(Baseline)
- Prevalence of moderate CAC in participants not taking low-cholesterol drug(Baseline)
- Correlation of CAC with the medical indication for PET imaging(Baseline)
- Prevalence of CAC in young participants (< 45 years old)(Baseline)
- Prevalence of no CAC in participants taking statins(Baseline)