A Comparative Study to Evaluate the Efficacy Of Haritaki and Dhanvyas in the Management Of Sthaulya (Obesity) w.s.r. to Antihyperlipidaemic Activity

Obesity/Overweight is a global epidemic resulting from sedentary lifestyles, improvedsocioeconomic conditions and availability of processed ,high calorie foods and soft drinks inindustrialized societies. Approximately 35% of US adult population is overweight, and anadditional 30 % of adults are obese; the prevalence of obesity in children and adolescents isalso increasing indeed reaching epidemic proportions . As obesity is correlated with increasedmorbidity and mortality , it is important to define and recognize it, to understand its causesand to be able to initiate appropriate measures to prevent or manage it. Behavioral and dietarychanges are the initial therapeutics strategies; weight loss drugs are used but due to theirside effects they are used with caution. Obesity is associated with an increased riskof multiple health problems, including hypertension, type-2 Diabetes, obstructive sleepapnea , dyslipidemia ,non-alcoholic fatty liver disease, degenerative joint disease. Thusit is important for its identification, evaluation and treatment so that associatedcomorbities doesn’t occur.Worldwide obesity has nearly tripled since 1975. In 2016, more than 1.9 billion adults, 18years and older, were overweight. Of these over 650 million were obese. 39% of adults aged18 years and over were overweight in 2016, and 13% were obese. Most of the world’spopulation live in countries where overweight and obesity kills more people thanunderweight. 39 million children under the age of 5 were overweight or obese in 2020.Over340 million children and adolescents aged 5-19 were overweight or obese in 2016. Pharmacology of Ayurvedic treatment on Sthaulya based on dissolving the accumulated fatby means of shoshana like sleshma-medohara ,ushna, trikshna aahara or drugs. Thedrugs which will replinsh or scrapes away the unwanted tissues (dhatus) and metabolicwastes (malas) is known as Lekhana. In Modern anti-hypercholesterolemia or anti-obesity like drugs are found to havemany adverse effects; hence it is the need of the hour to find an alternative drug in other10systems of medicine. Although a number of research works and studies have been done onthe treatment of Sthaulya (Obesity), still there is an intense need for the effectivemanagement of this dreadful disease. In this view the study has been selected to establishanti-obesity drugs and having anti-hyperlipidemic activity by using the Haritaki(Terminaliachebula) (Roxb.) mentioned in Charak samhita under Santarpaneeya adhyaya and in Ashtanghridya under Dwividho opkramneeya adhyaya containing Sthaulyanashakproperties.Dhanvyas(Fagonia cretica{Linn.}) mentioned in Bhavprakash Nighantu havingmedovikarhar properties.