Microscopy Imaging of Whole-mount Stained Human Tissues: Development of an Imaging Platform for Intraoperative Tumor Margin Delineation
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 250
- 试验地点
- 1
- 主要终点
- The assessment between tumor cases and control cases
研究概览
简要总结
The goal of this clinical trial is to develop an imaging platform for intraoperative tumor margin delineation in 250 cases of tumor-suffered patients. The main questions it aims to answer are:
• to develop the protocol of rapid assessment of surgical specimens without need for fixation, embedding, and cryosectioning required for conventional histopathology.
Participants will provide a small piece of their surgical specimens from tumor removal surgery .
If there is a comparison group: Researchers will compare normal specimens to see if we can observe the difference.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients who are more than 20 years old.
- •Diagnosed as patients suffered by skin tumor, brain tumor and breast tumor.
排除标准
- •Patients who can't speak and communicate with others.
- •Patients who can't make eventual and exact pathological assessment for his/her diseases.
- •Patients who only can fit for slicing tumor.
- •Removed tissues which obviously vary after severe ray radiation under microscopy observation.
- •Diameter of tumors are under 1 centimeter.
- •Breast carcinoma in situ.
结局指标
主要结局
The assessment between tumor cases and control cases
时间窗: 5 years
Do comparison with images acquired by our microscopy (with the whole-mount staining method) and bright field microscopy (with standard FFPE method) and do assessment to interpret tumor characteristics
次要结局
未报告次要终点