Carbohydrate Loading Before and Intermittent High Carbohydrate Intake During Prolonged Physical Exercise in Individuals With Type 1 Diabetes is Associated With Good Glucose Control
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 10
- 主要终点
- The percentage of the glucose values spent in target range, defined as 72-180 mg/dl.
研究概览
简要总结
Prolonged physical exercise (PE) is a challenge in type 1 diabetes with an increased incidence of both hypoglycemia and hyperglycemia.
The purpose was to evaluate the impact of two consecutive days of carbohydrate (CHO) loading, followed by high intermittent CHO-intake during prolonged PE, facilitated by a proactive use of Real-Time Continuous Glucose Monitoring (rtCGM), on glucose control in individuals with type 1 diabetes.
Ten physically active individuals with type 1 diabetes were invited to participate in a 3-day long sports camp with the objective to evaluate CHO-loading and high intermittent CHO-intake during prolonged PE. 1.5 months later the same procedure was evaluated during a 90 km cross-country skiing race. Participants were instructed to act proactively using rtCGM with predictive alerts set for high and low glucose values to maintain sensor glucose values within target range, defined as 72-180 mg/dl (4-10 mmol/l).
详细描述
This is a descriptive, single arm, non-randomized interventional study. The intervention consisted of carbohydrate loading prior to and intermittent high carbohydrate intake during physical exercise and a proactive use of Real-Time Continuous Glucose Monitoring (rtCGM) to achieve and maintain glucose control.
Central Contact Person Stig A Mattsson, dietician PhD student Phone: +46702047759 E-mail: stigmattsson@live.com
IPD Sharing Statement No: There is not a plan to make IPD available.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •age 18-50 years
- •type 1 diabetes
- •diabetes duration >1 year
- •exercising regularly ≥3 workout/week
- •previous experience from cross-country skiing
排除标准
- •A1c 8.6% NGSP (70 mmol/mol IFCC)
- •proliferative retinopathy
- •known nephropathy
- •cardiac failure
- •following a low-carbohydrate diet.
研究组 & 干预措施
Descriptive, single arm, interventional study
The intervention consisted of carbohydrate loading prior to and intermittent high carbohydrate intake during physical exercise and a proactive use of Real-Time Continuous Glucose Monitoring (rtCGM) to achieve and maintain glucose control
干预措施: Carbohydrate loading and high intermittent carbohydrate intake during physical exercise (Other)
结局指标
主要结局
The percentage of the glucose values spent in target range, defined as 72-180 mg/dl.
时间窗: Through 48 hours of carbohydrate loading and an average of 6.5 hours of cross-country skiing.
次要结局
未报告次要终点