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临床试验/NCT03986112
NCT03986112Unknown不适用

Ability of Carotid Sonography and Inferior Vena Cava Sonography for the Prediction of Post-induction Hypotension in Hypertensive Patients

Yonsei University1 个研究点 分布在 1 个国家目标入组 58 人开始时间: 2019年7月最近更新:
适应症

试验速览

阶段
不适用
入组人数
58
试验地点
1
主要终点
Prediction power of the post-induction hypotension of carotid sonography and inferior vena cava sonography

研究概览

简要总结

Hypertensive patients have more hemodynamic instability during general anesthesia than do patients with NORMOTENSION. In this study, the investigators evaluated the usefulness of carotid ultrasound and inferior vena cervical ultrasound for predicting hypotension after induction of anesthesia in patients with hypertension.

详细描述

Carotid and venous ultrasonography is performed in a comfortable state. Corrected blood flow after carotid ultrasound and carotid artery blood flow rate were measured.

After inferior vena cava sonography, using the embedded software, the collapsibility Index by measuring the largest and smallest diameter during the respiratory cycle will be obtained.

After confirming baseline blood pressure and pulse rate, propofol 2 mg / kg is administered and remifentanil is maintained at 4.0 ng / mL using the Target Control System (TCI).

Following the administration of rocuronium 1.0-1.2 mg / kg, and 1 minute and 30 seconds after BIS 60 or less, endotracheal intubation is performed using video laryngoscope.

Blood pressure and heart rate are measured at prior to induction, 1 minute after the induction, immediately after intubation, and at 1, 3, 5, 7 and 10 minutes after intubation.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Prospective

入排标准

年龄范围
19 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • 19-80 years old hypertensive patients with ASA class I-III
  • Scheduled surgery under general anesthesia

排除标准

  • Emergency operation
  • Reoperation
  • Patients with history of heart failure (unstable angina, congestive heart failure, coronary artery disease)
  • Patients under 40 % of Ejection faction
  • Patients with history of valvular heart failure
  • Patients with history of peripheral arterial occlusive disease
  • Patients with history of arrhythmia (specially AV nodal block), ventricular conduction problem
  • Pregnancy patients
  • Patients who cannot read the consent form (examples: Illiterate, foreigner)
  • Patients with history of uncontrolled psychiatric disease (PTSD, anxiety, depression)
  • Patients who withdraw the consent

结局指标

主要结局

Prediction power of the post-induction hypotension of carotid sonography and inferior vena cava sonography

时间窗: 10 minutes after tracheal intubation

To evaluate the ability of carotid sonography and inferior vena cava sonography for the post-induction hypotension in hypertensive patients undergoing general anesthesia, blood pressure was measured 10 minutes after tracheal intubation.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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