Effectiveness of Chlorhexidine Wipe for Prevention of Multidrug-resistant Organisms in Intensive Care Unit Patients
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 481
- 试验地点
- 1
- 主要终点
- The overall rate of Multidrug resistant bacteria acquisition at 7 days after received 2% chlorhexidine wipe bathing versus with soap bathing
研究概览
简要总结
The purpose of this study is to determine 2% chlorhexidine wipes are effective in preventing of colonization of multi-drug resistant bacteria in intensive care unit patients.
详细描述
The purpose of this study is to evaluate the usefulness of bathing with chlorhexidine wipe to reduce the risks of multidrug resistant bacteria acquisition and hospital-acquired bloodstream infection among ICU patients
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 95 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age > 18 years
- •Admission in critical care unit eg. ICU, respiratory care unit, Cardiac care unit with in 24 hours
- •Expected duration of critical care unit admission > 48 hours
排除标准
- •History of chlorhexidine allergy
研究组 & 干预措施
Soap bathing
ICU patients will be bathing with soap at least once daily
干预措施: Soap (Drug)
2% chlorhexidine wipes
Use 2% chlorhexidine wipes to clean the patient at least once daily
干预措施: 2% chlorhexidine wipe (Drug)
结局指标
主要结局
The overall rate of Multidrug resistant bacteria acquisition at 7 days after received 2% chlorhexidine wipe bathing versus with soap bathing
时间窗: 7 days after recieved 2% chlorhexidine wipes
7 days after received 2% chlorhexidine wipes,the microbiology laboratory will process surveillance specimens using either standard culture-based at both nostrils, axillar, groins, rectum
次要结局
- The overall rate of hospital-acquired bloodstream infections per 1000 patient-days with chlorhexidine wipe bathing versus with soap bathing(48 hours after recieved 2% chlorhexidine wipes)
研究者
Adhiratha Boonyasiri
Doctor
Mahidol University