Plasticity in brain circuits underlying interactions between pain and depression

Zentralinstitut für Seelische Gesundheit (ZI)0 个研究点目标入组 250 人开始时间: 2016年5月23日最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•For all subjects:
•- Sufficient german language abilities
•- Ability to consent
•- Residence in Mannheim or within a 50 km radius
•For healthy controls
•- No diagnosis of any psychiatric disorder according to ICD-10 and DSM-IV
•- No family history of any psychiatric disorder according to ICD-10 and DSM-IV
•For healthy first grade relatives:
•- No diagnosis of any psychiatric disorder according to ICD-10 and DSM-IV
•- First grade relative of patients with the diagnosis of MD according to ICD-10 or DSM-IV
•For patients:
•- Diagnosis of MD according to DSM-IV or V

•Exclusion Criteria:
•- Participant unable to content
•- Acut exacerbated psychosis or psychiatric comorbidity, which needs clinical or pharmacological treatment
•- Change in psychopharmacological treatment in the last 8 weeks
•- Substance abuse except for nicotine
•- For healthy controls and first degree relatives: psychiatric disorder according to ICD-10 or DSMIV
•For the stepwise procedure additional exclusion criteria for the MRI:
•- For women: pregnancy
•- MR exclusion criteria (e.g. claustrophobia, pacemaker, artificial heart valves, cochlear implants, intracranial vessel clip, metal implants, brain surgery, permanent makeup, large scale tattoos on head or nape)

发起方