NCT07133204已完成不适用
Study of Efficacy and Safety of Cream Infused With HuangQin (Root of Scutellaria Baicalensis) Extract for the Reduction of Hyperpigmentation
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 38
- 试验地点
- 2
- 主要终点
- Efficacy of hyperpigmentation reduction property of the intervention
研究概览
简要总结
The aim of this study is to evaluate the efficacy of a topical cream infused with Scutellaria baicalensis extract in reducing hyperpigmentation on the face.
The study is experimental clinical pilot study as a single group pretest-posttest.
A ROAT is conducted 1 week prior to the experiment. Participant apply the cream on the hypigmented area daily. Facial skin parameters (i.e. melanin index, erythema index) is evaluated at week 0, 1, 2 and 4.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 30 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Male or Female
- •Has at least 1 hyperpigmentation spot (size > 3mm) on either side of the face
- •30-60 y/o
- •Fitzpatrick skin types II-IV
- •Agrees to use sunscreen SPF50+ and willing to avoid strong sunlight exposure during the study
排除标准
- •Pregnant or lactating
- •Use of whitening products or treatment within 1 month before this study
- •Currently using contraceptives
- •History of allergy to any ingredient in the intervention cream
- •Has skin conditions which can interfere with the measurement (i.e. severe acne, eczema, herpes simplex)
- •Severe disease (i.e. immunodeficiency, cancer)
- •Enrolled in other clinical study within 3 month before this study
结局指标
主要结局
Efficacy of hyperpigmentation reduction property of the intervention
时间窗: Week 0, 1, 2 and 4
Measured the melanin index of the hyperpigmented area
Safefty profile of the intervention
时间窗: Week 1, 2 and 4
Record and collect the adverse effect from the usage of the interventional cream
次要结局
- Efficacy of erythema reduction property of the intervention(Week 0, 1, 2 and 4)
- Efficacy of skin hydration property of the intervention(Week 0, 1, 2 and 4)
研究者
研究点 (2)
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