A Prospective Randomized Double Blind Clinical Trial to Assess the Efficacy of Twin Mix and Lidocaine on Inferior Alveolar Nerve Block in Patients with Irreversible Pulpitis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Twin Mix may prove to be an effective anesthetic in cases of Irreversible Pulpitis
研究概览
简要总结
Achieving successful pulpal anaesthesia in healthy mandibular teeth is a challenge for the practitioner, with a success rate of 51-65% . There have been multiple suggestions to control this pain :
- Supplementary anaesthesia –
Intraligamentary
Intraosseous
Intrapulpal
-
buccal infiltrations of articaine, ketarol, dexamethasone
-
Premedication with analgesics and steroids ( Ibuprofen, Ketarol, Dexamethazone )
Use of steroid as oral, parental and submucosal routes has been extensively studied in third molar impaction surgeries.
One method of delivery suggested is mixing the steroid in the LA solution – TWIN MIX
This mixture has been extensively studied and found to be very effective .
The efficacy in teeth with irreversible pulpitis has not been studied
The aim of this study is to assess the anaesthetic efficacy of twin mix for achieving successful pulpal anaesthesia when used in IANB, and in cases of irreversible pulpitis.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 50.00 Year(s)（—）
- 性别
- All
入选标准
- •Age: 18-50 years
- •Currently feeling pain:
- •Good health
- •Not taking any medication that would alter the perception of pain determined by verbal questioning and written questionnaire.
- •Patient has to be clinically diagnosed with irreversible pulpitis on the basis of
- •Moderate to severe spontaneous pain
- •Prolonged response to cold testing and
- •Positive response to the electric pulp test.
排除标准
- •Existence of acute infection and/or swelling Systemic disorders History of complications associated with LA.
结局指标
主要结局
Twin Mix may prove to be an effective anesthetic in cases of Irreversible Pulpitis
时间窗: The result will be evaluated in 25 minutes after injection
次要结局
- Twin Mix may prove to be more effective as compared to Lidocaine in cases of Irreversible Pulpitis(Routine Clinical Application)