An Assessment of Hematologic Diseases Among Blood Transfusion Recipients and Donated Units at a Pediatric Regional Referral Hospital in Uganda
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 250
- 试验地点
- 1
- 主要终点
- Frequency of Sickle Cell Anemia
研究概览
简要总结
This study looks at why some children develop very severe anemia that leads to a blood transfusion. It also checks for diseases in the blood they receive. Researchers are using small samples of dried blood (called dried blood spots) from both the children and the donated blood to find out what might be causing the anemia.
详细描述
This study includes children at Jinja Regional Referral Hospital (Jinja, Uganda) who need a blood transfusion, whether they are in the clinic, emergency room, or children's ward. After doctors finish the usual blood tests, a small sample of leftover blood will be saved on a special card (called a dried blood spot). The same will be done for all blood transfused during the study. These samples will be frozen and later sent to Cincinnati Children's Hospital for testing.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Children receiving a blood transfusion in Eastern Uganda at Jinja Regional Referral Hospital.
排除标准
- •If receiving a blood transfusion, refusal or inability to sign an informed consent.
结局指标
主要结局
Frequency of Sickle Cell Anemia
时间窗: At enrollment.
How common sickle cell anemia is in children who need a blood transfusion in Eastern Uganda.
次要结局
- Frequency of Malaria Parasitemia(At enrollment.)
- Frequency of Iron Deficiency(At enrollment)
- Blood Group Markers(At enrollment.)