Sport and Health a Pilot Study: Impact of Endurance Physical Activity on the Microbiological Homeostasis of the Oral Cavity of Young Adults
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 103
- 试验地点
- 2
- 主要终点
- Analysis of the oral microbiota in healthy individuals engaged in endurance physical activity at different levels.
研究概览
简要总结
The oral cavity is an easily accessible anatomical site that accurately reflects the health of the individual. The mouth is considered an early indicator of biological aging, leading to the identification of oral biomarkers predictive of future alterations. Current data show that the oral health of high level athletes is globally altered with an increase in cariogenic indexes, an increased incidence of periodontitis, dental trauma and dry mouth syndromes. Few studies have focused on the oral microbiota compared to mouthguards used in rugby or boxing which seem to induce dysbiosis, a recent study shows an effect of ketogenic diet on bacterial changes in the mouth of endurance athletes. This project focuses on the impact of intensive sport practice on oral health and the identification of oral biomarkers associated with physical activity. The objective of this study is to investigate the impact of the amount of endurance sport practice on oral microbiota and oral health in young adults. the hypothesis is that a sedentary lifestyle and high-level sport induce depletion and/or changes in the oral microbiota compared to regular physical activity.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 30 Years(Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Be between 18 and 30 years old
- •If practicing sports, it must be an endurance sport as main activity (cycling or running)
排除标准
- •Practice more than 3 hours of swimming per week
- •Have taken anti-inflammatory drugs, less than 48 hours before the study
- •Have taken antibiotics and/or probiotics, less than 3 weeks before the study
研究组 & 干预措施
sedentary
Participant does not meet WHO's recommendations with the physical activity
干预措施: salivar and gum sampling (Other)
OMS recommandations
Participant does not meet WHO's recommendations (2.5-5 hours per week of moderate physical activity OR 1.25-2.5 hours per week of vigorous physical activity);
干预措施: salivar and gum sampling (Other)
More than the OMS recommandations
Participant is practicing physical activity more than the WHO recommendations
干预措施: salivar and gum sampling (Other)
结局指标
主要结局
Analysis of the oral microbiota in healthy individuals engaged in endurance physical activity at different levels.
时间窗: 3 years
Microbiological screening will be performed using an innovative methodology based on microfluidic PCR (BiomarkHD) (number of bacterial colonies)
次要结局
- Quantification of salivary inflammatory markers in healthy individuals who perform endurance physical activity at different levels.(3 years)
