ACTRN12614000821695已完成1 期
Study to assess the safety of hypofractionated radiotherapy with concurrent carboplatin and paclitaxel in palliative management of esophageal cancers.
适应症
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 入组人数
- 18
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Non-randomised trial
- 主要目的
- Treatment
入排标准
- 年龄范围
- 18 Years 至 o limit（—）
- 性别
- All
入选标准
- •1.Histologically proven squamous cell carcinoma or adenocarcinoma of the esophagus or gastro-esophageal junction.
- •2.Symptomatic with Mellow dysphagia score of at least 1.
- •3.Patients not considered amenable to curative surgery or radical chemoradiotherapy due to either patient-related factors or advanced esophageal cancer stage (locoregional lymphadenopathy and/or low volume metastatic disease).
- •4. ECOG performance status 0-2.
- •5. No contraindication to receiving weekly carboplatin or paclitaxel chemotherapy including adequate bone marrow function.
- •6. Above 18 years old.
排除标准
- •1.Previous thoracic radiotherapy.
- •2.Tracheo-esophageal fistula.
- •3.Esophageal stents in situ.
- •4.Previous chemotherapy for esophageal cancer.
- •5.Presence of bulky or organ-threatening metastatic disease requiring immediate higher dose chemotherapy.
- •6.Pregnant patients.
研究者
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