Trends of Morbidity and Mortality Among Thai HIV-infected and HIV-uninfected Patients: a Five-year Prospective Cohort Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 816
- 试验地点
- 1
- 主要终点
- morbidity
研究概览
简要总结
- To describe the morbidity and clinical characteristics among HIV-infected patients and HIV-uninfected patients.
- To identify the risk factors for the complication or morbidity among HIV-infected patients and HIV-uninfected patients.
- To describe the mortality among HIV-infected patients and HIV-uninfected patients.
- To identify the risk factors for the cause of death among HIV-infected and HIV-uninfected patients.
详细描述
The information obtained from this study would be very important in planning future holistic care of HIV-infected patients in our institutes as well as in national policy. Results from the study could be used to develop proper long-term management guidelines for people living with HIV (PLHIV) in Thailand targeted at preventable conditions such as metabolic diseases and certain cancers.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 30 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •HIV-infected patients group
- •HIV positive
- •30 years of age or older, both male and female
- •Thai nationality
- •Written research informed consent
- •HIV-uninfected patients group
- •HIV un-infected
- •30 years of age or older, both male and female
- •Thai nationality
- •Written research informed consent
排除标准
- •HIV-infected patients group
- •Systolic BP ≥ 130 or Diastolic BP ≥ 85mm Hg or on the treatment
- •Fasting blood sugar > 126 mg/dl or on the treatment
- •Proteinuria
- •Creatinine > 1.5 mg/dl
- •Recent hospitalization
- •Patient who are having mental disease HIV-uninfected patients group
- •Systolic BP ≥ 130 or Diastolic BP ≥ 85mm Hg or on the treatment
- •Fasting blood sugar > 126 mg/dl or on the treatment
- •Proteinuria
- •Creatinine > 1.5 mg/dl
- •Recent hospitalization
- •Patient who are having mental disease
结局指标
主要结局
morbidity
时间窗: 60 months
development of other diseases
HIV related illness
时间窗: 60 months
development of opportunistic infection such as Non-Hodkin's lymphoma, Kaposi's sarcoma
Non HIV-related illness
时间窗: 60 months
development of Dyslipidemia, Hypertension, DM, CVD , Cancer, osteopenia, osteoporosis, Renal disease, liver disease
CVD
时间窗: 60 months
development of CVD
mortality
时间窗: 60 months
death
次要结局
未报告次要终点