NCT06384703已完成不适用
The Evaluation of the Relationship Between Coronary Ectasia And Trimethylamine N Oxide
Konya Beyhekim Training and Research Hospital1 个研究点 分布在 1 个国家目标入组 2 人开始时间: 2020年11月3日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 2
- 试验地点
- 1
- 主要终点
- death
研究概览
简要总结
Introduction: It is now known that the microbiota is far beyond the microbial communities living in certain parts of our body and functions like a metabolic organ. In addition, the microbiota, through its metabolites, is involved in the pathophysiology or progression of a wide range of diseases, from atherosclerotic diseases to metabolic diseases and even neurological diseases. Among these metabolites, trimethylamine n-oxide metabolite has been shown to be particularly effective on atherosclerotic heart diseases.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •over 18 years old
- •not having occlusive coronary artery disease
- •having coronary ectasia
排除标准
- •patients with chronic kidney disease,
- •revascularized coronary artery disease,
- •previously documented critical coronary stenosis,
- •acute or chronic inflammatory disease,
- •rheumatologic disease,
- •known active malignant disease,
- •heart failure,
- •moderate-to-severe valvular pathology
- •patients who were on any steroid or immunosuppressive therapy
结局指标
主要结局
death
时间窗: 1 month
Death from any cause within the last month
次要结局
未报告次要终点
研究者
研究点 (1)
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