IRCT20230508058120N1招募中Unknown
Comparison of the effects of vitamin D and N-acetylcysteine supplementation on the expression of cellular senescence genes and inflammatory factors in the elderly with vitamin D deficiency. A double-blind randomized clinical trial
适应症
试验速览
- 阶段
- Unknown
- 状态
- 招募中
- 入组人数
- 100
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 65 years 至 no limit（—）
- 性别
- All
入选标准
- •Elderly people with a body mass index of 25-32 kg/m2
- •Serum vitamin D deficiency (less than 30 ng/mL)
- •Age over 65 years old
- •No chronic and acute inflammatory and infectious diseases
- •Not suffering from diabetes and thyroid diseases
- •Not suffering from Alzheimer's and dementia
- •Not receiving alcohol and smoking
- •Not receiving medication or a disorder that affects vitamin D metabolism (anticonvulsant drugs, antituberculosis drugs, glucocorticoids, HIV drugs)
- •Not receiving vitamin D and N-acetyl cysteine and antioxidant supplements in the last three months
- •Non-participation in other clinical trial studies at the same time as the present study
排除标准
- •Hypercalcemia (more than 2.6 mmol/L)
- •Dysparathyroidism, kidney failure and stones, and long-term treatment with bisphosphonates and corticosteroids.
- •Consumption of less than 90% of prescribed supplements
- •Unwillingness to cooperate during the intervention
研究者
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