JPRN-jRCT1051200028招募中2 期
Phase II trial on Programmed death-One inhibitor plus RadioThERapy in patients with Metastatic Mucosal Melanoma - PORTER-M3 trial
omura Motoo0 个研究点目标入组 20 人开始时间: 2020年6月22日最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 招募中
- 发起方
- 入组人数
- 20
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- >= 20age old 至 ot applicable（—）
- 性别
- All
入选标准
- •1) Histologically proven mucosal melanoma
- •2) Aged 20 years old or more
- •3) metastatic disease
- •4) No previous treatment for metastatic mucosal melanoma
- •5) ECOG PS of 0 or 1
- •6) Need for measurable lesion
- •7) Adequate organ functions
- •8) Written informed consent
排除标准
- •1) Synchronous or metachronous (within 5 years) malignancies except for carcinoma in situ or mucosal tumors curatively treated with local therapy.
- •2) The current radiation field do not overlap the previous radiation field.
- •3) Active infection requiring systemic therapy.
- •4) Patients with immune suppression.
- •5) Patients with central nerve system metastases.
- •6) Patients with complications of autoimmune disease, histories of chronic and recurrent autoimmune disease or other diseases which require systemic steroid therapy or immune suppressor.
- •7) Patients received live vaccines.
- •8) Pregnancy, possible pregnancy or breastfeeding.
- •9) Psychiatric disease.
- •10) Patients requiring systemic steroid medication.
- •11) Severe pulmonary fibrosis or emphysema.
- •12) Patients whom principle/sub-investigator judged ineligible to participate in this study.
研究者
相似试验
已完成
2 期
Phase II trial on Programmed death-One inhibitor plus RadioThERapy in patients with Metastatic Mucosal MelanomaMetastatic Mucosal MelanomaJPRN-UMIN000030533Kyoto University20
终止
2 期
A clinical research study testing olaparib, in Homologous recombination (HR) deficient metastatic breast and relapsed ovarian cancer in patients who do not have hereditary mutations in BReast CAncer susceptibility gene 1 and gene 2 (BRCA1 and BRCA2)ACTRN12617000855325niversity of Sydney22
已完成
不适用
A trial to study of treatment with a new PPI for infection of H. pylori with Clarithromycin resistanceChronic gastritis infected by H. pylori with Clarithromycin resistanceJPRN-UMIN000018595ippon Kokan Fukuyama Hospital100
已完成
1 期
A clinical trial of influenza(H1N1) vaccine (Live attenuated) in Adults.CTRI/2010/091/000008Serum Institute of India Limited50
招募中
4 期
The CORINTH Trial: Study of Checkpoint Inhibitor Pembrolizumab plus standard chemoradiation in anal cancerAnal cancer2024-515369-33-00Cardiff University3