Robotic -Assisted Rehabilitation for Multiple Sclerosis: An Adaptive Approach for Individualized Therapy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 9
- 试验地点
- 1
- 主要终点
- Maximum isometric wrist force
研究概览
简要总结
Therefore, the purpose of this study was to evaluate four-weeks of an upper limb robotic intervention for persons with Multiple Sclerosis. Participants completed a resistive and adaptive robotic training intervention whereby participants trained three times weekly for four consecutive weeks.
详细描述
Nine individuals with Multiple Sclerosis participated and were placed into two groups based that either trained their self-reported less affected limb (indirect training group; N=4) or trained their self-reported more affected limb (direct training group; N=5).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosis of MS
- •No other neurological diagnosis
- •No injury to the upper limb (i.e., broken bones)
排除标准
- •Relapse in the past 6 months
研究组 & 干预措施
Indirect training group
trained their self-reported less affected upper limb
干预措施: end-effector robotic training (Device)
Direct training group
trained their self-reported most affected limb
干预措施: end-effector robotic training (Device)
结局指标
主要结局
Maximum isometric wrist force
时间窗: Baseline (Week 0) and immediately post intervention (Week 4)
the participant's arm was fully extended and rested on the table, and participants were instructed to exert force at the wrist joint (F/E, RD/UD) as hard as they could against the stationary load cell that rested on the metacarpophalangeal joints (Model: BG 500, Mark-10 Corporation, New York, USA). Two maximal exertions were completed and the largest value was recorded.
maximum grip force
时间窗: Baseline (Week 0) and immediately post intervention (Week 4)
Participants were asked to complete one trial of a maximum grip test (Baseline Evaluation Instruments). Held with a straight arm, 45° abduction by the side and hand/wrist neutral, participants were asked to squeeze the handle as hard as possible for 3 seconds and grip force (Newton) was recorded.
Maximum isometric wrist force
时间窗: Baseline (Week 0) and immediately post intervention (Week 4)
the participant's arm was fully extended and rested on the table, and participants were instructed to exert force at the wrist joint (F/E, RD/UD) as hard as they could against the stationary load cell that rested on the metacarpophalangeal joints (Model: BG 500, Mark-10 Corporation, New York, USA). Two maximal exertions were completed and the largest value was recorded.
次要结局
- Wrist tracking task(Baseline (Week 0) and immediately post intervention (Week 4))
- wrist range of motion(Baseline (Week 0) and immediately post intervention (Week 4))
- Wolf Motor Function Test(Baseline (Week 0) and immediately post intervention (Week 4))
- Wolf Motor Function Test(Baseline (Week 0) and immediately post intervention (Week 4))
- Wrist tracking task(Baseline (Week 0) and immediately post intervention (Week 4))
- wrist range of motion(Baseline (Week 0) and immediately post intervention (Week 4))
研究者
Michael Holmes
Associate Professor
Brock University