MRI CSF FLOW STUDY PARAMETERS IN CASES OF INCREASED AND DECREASED INTRACRANIAL PRESSURE- COMPARISON WITH NORMAL CONTROLS

DEPARTMENT OF RADIODIAGNOSIS0 个研究点目标入组 80 人开始时间: 待定最近更新: 2021年11月24日

试验速览

暂无简介。

•CONTROLS: Volunteers referred for MRI for indications other than conditions causing increased or decreased intracranial pressures with age ranging from 18 to 80 years.
•Participants are recruited after the routine MRI/CT study shows suspicion or indeterminate results (i.e. discrepancy with clinical findings) and are then taken up for few special flow MRI sequences which require extra 12 minutes (apart from the routine protocol).
•The informed consent is taken at the MRI console.
•Enrolment in NPH group: Patients with clinical and imaging features of NPH and/or a positive tap test.
•Enrolment in diffuse cerebral atrophy group: Patients with imaging features typical of cerebral atrophy with no clinical or imaging features suggestive of NPH.
•Enrolment in hydrocephalus group: Patients with hydrocephalus caused by periaqueductal or fourth ventricular obstruction as seen on conventional CT/MR.
•Enrolment in benign intracranial hypertension group: Patients presenting only with papilledema with normal MR imaging.
•Enrolment of patients with clinical conditions resulting in CSF hypovolemia:
•True hypovolemic state
•CSF shunt over drainage
•Traumatic CSF leaks
•Iatrogenic CSF leaks (post dural puncture/post-surgical leaks)
•Spontaneous CSF leaks.
•With routine MRI or clinical follow-up suggesting CSF hypovolemia.

发起方

DEPARTMENT OF RADIODIAGNOSIS