NCT00730860Unknown不适用
Treatment of Hepatocellular Carcinoma With Radiofrequency Ablation Associated With Postoperative Transhepatic Arterial Chemoembolization--a Prospective Randomized Clinical Trial
Southwest Hospital, China1 个研究点 分布在 1 个国家目标入组 140 人开始时间: 2009年12月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 140
- 试验地点
- 1
- 主要终点
- disease free survival
研究概览
简要总结
A RCT was conducted to elucidate whether the treatment outcome of HCC could be improved by RFA associated with postoperative TACE.
详细描述
A randomized study was conducted to elucidate whether the outcome of hepatocellular carcinoma could be improved by radiofrequency ablation associated with postoperative transhepatic arterial chemoembolization.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients with hepatocellular,confirmed by pathological examination
- •patients with a live function test showed Child A or B
- •Indocyanine green test showed less than 30％ after 15min,and the patients showed a tolerance of RFA and TACE
- •Tumor stage is early period(according to Milan Standard),that is,the diameter of single node should be less than 5cm；the node of tumor should be less than 3 and the diameter less than 3cm.
- •without metastasis in lymphnode or other organs
- •written consent inform assigned
排除标准
- •preoperative examination showed malignant thrombosis in the first class branch of portal vein or hepatic vein or vena cava
- •metastatic cancer of liver
- •patients with a poor tolerance of RFA and TACE
- •patients received other therapies.
结局指标
主要结局
disease free survival
时间窗: 3 years
次要结局
- overall survival(3 years)
研究者
feng xiaobin
Dr Xiaobin Feng
Southwest Hospital, China
研究点 (1)
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