IRCT138809051475N4已完成早期 1 期
Pilot study of efficacy of topical nano-liposomal meglumine antimoniate (Glucantime) or paromomycin in combination with systemic Glucantime for the treatment of anthroponotic cutaneous leishmaniasis (ACL) caused by Leishmania tropica
适应症
试验速览
- 阶段
- 早期 1 期
- 状态
- 已完成
- 入组人数
- 30
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 12 years 至 60 years（—）
- 性别
- All
入选标准
- •1.Male or female aged between 12 to 60 years.
- •2.Parasitologically proven CL due to L. tropica.
- •3.History of failure to at least one full course of systemic Glucantime.
- •4.In general good health based on history and physical examination.
- •5.Number of lesion at most 4.
- •6.Lesion size less than 3 cm.
- •7.Signed informed consent voluntarily and knowingly**.
- •** Guardian’s signature for volunteer less than 18 years old.
- •Exclusion criteria:
- •1.Pregnant or lactating women and those who are planning to be pregnant in next 60 days.
- •2.Use of other types of treatment for CL.
- •3.Involvement in any other drug or vaccine trial during the study period.
- •4.Known heart, kidney, liver diseases based on history and physical exam.
- •5.Abnormal ECG
排除标准
- 未提供
研究者
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