Evaluation of Transpharyngeal Doppler Sonography as a Cerebral Monitoring Tool in Cardiac Surgery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- Accuracy of cerebral flow velocity measurement
研究概览
简要总结
This prospective interventional study investigates transpharyngeal sonography (TPS) as an additional neuromonitoring strategy to assess cerebral perfusion during cardiovascular surgery. In the first part of the study the investigators will investigate the feasibility of TPS for visualization of aortic arch branches including the innominate and the carotid arteries in patients undergoing cardiac surgery with cardiopulmonary bypass. In the second part the investigators plan to adopt the investigators previous experiences on TPS to a selected population of patients undergoing ascending aortic and/or arch repair in hypothermic circulatory arrest (HCA).
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Sequential
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Cardiovascular Surgery
- •Age > 18 yrs
- •Informed Consent
排除标准
- •Contraindication for TPS
- •Carotid artery stenosis
研究组 & 干预措施
20 patients (1-20) validation arm
Accuracy of cerebral flow measurement between TPS and CDS in 20 patients undergoing cardiovascular surgery with cardiopulmonary bypass
干预措施: Transpharyngeal Doppler sonography (TPS) (Diagnostic Test)
20 patients (1-20) validation arm
Accuracy of cerebral flow measurement between TPS and CDS in 20 patients undergoing cardiovascular surgery with cardiopulmonary bypass
干预措施: Conventional colour-coded Duplex sonography (CDS) (Diagnostic Test)
20 patients (21-40) HCA arm
Assessment and comparison of TPS and CDS in hypothermic circulatory arrest (HCA) during cardiovascular surgery
干预措施: Transpharyngeal Doppler sonography (TPS) (Diagnostic Test)
20 patients (21-40) HCA arm
Assessment and comparison of TPS and CDS in hypothermic circulatory arrest (HCA) during cardiovascular surgery
干预措施: Conventional colour-coded Duplex sonography (CDS) (Diagnostic Test)
结局指标
主要结局
Accuracy of cerebral flow velocity measurement
时间窗: intraoperative phase, expected to be ca. 4 hours
Cerebral blood flow velocity measurements will be performed with transpharyngeal Doppler sonography (TPS) and conventional colour-coded Duplex sonography (CDS). Doppler flow velocities (obtained at the same intraoperative phase and at the same time) will be compared between TPS and CDS TPS and different Doppler techniques.
次要结局
- Hypothermic Circulatory Arrest(intraoperative phase, expected to be ca. 4 hours)