NL-OMON54345尚未招募2 期
Safety and feasibility of CT-guided percutaneous radionuclide therapy with the OncoSil* device in patients with non-progressive locally advanced pancreatic cancer (PANCOSIL): an open-label, single-arm phase 1-2 feasibility study - PANCOSI
适应症
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 入组人数
- 20
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •- Age >=18 years
- •- Locally advanced pancreatic cancer, defined by the DPCG consensus criteria
- •as: arterial involvement >90* or venous involvement >270*.
- •- At least RECIST stable disease after a minimum two months of chemotherapy
- •according to current clinical practice*
- •- Capable of providing written and oral informed consent
- •- Candidate for RNT, judged by a multidisciplinary tumor board
- •- WHO 0-2
- •* FOLFIRINOX for patients with WHO 0-1 performance status and
- •gemcitabine-nab-paclitaxel for patients with > 1-2performance status.
排除标准
- •- Eligibility for resection
- •- Participation in other trials focussing on different ablative treatment
- •modalities such as radiofrequency ablation or irreversible electroporation for
- •- Bleeding disorders which cannot be corrected with medication
- •- Inability/unwillingness to interrupt anticoagulation therapy
- •- Pregnancy
- •- Metastatic pancreatic cancer
- •- Epilepsy episode(s) in the past six months
- •- Longest tumor diameter >70 mm or total target tumor volume >110 ml
- •- Presence of multiple collateral vessels surrounding or adjacent to the target
- •tumor on radiologic imagining, prohibiting safe injection of the OncosilTM
- •- Presence (or significant risk) of varices near the target tumor on radiologic
- •- Recent clinically significant pancreatitis
- •- Previous administration of radiotherapy to the pancreas
- •- WHO > 2
研究者
相似试验
已完成
不适用
Feasibility of CT-guided percutaneous needle puncture for kidneys with CASone systemkidney stonesnephrolithiasis10046708NL-OMON51258Radboud Universitair Medisch Centrum10
招募中
Unknown
Robotic-assisted CT-guided puncture studyJPRN-jRCTs042220084Ohta Kengo60
已完成
不适用
Safety and efficacy of the transradial percutaneous coronary intervention using sheathless guiding catheters for acute coronary syndrome: A radial ultrasound follow-up studyAcute coronary syndromeJPRN-UMIN000019931Sendai Kousei Hospital500
已完成
不适用
Therapeutic value of CT-guided periradicular and facet joint infiltrations in patients with chronic low back pain and radiculopathyM47.26M51.1Lumbar and other intervertebral disc disorders with radiculopathyDRKS00023722niversitätsklinikum Jena250
已完成
不适用
Clinical efficacy and safety of percutaneous transhepatic portal embolization (PTPE) with N-butyl 2-cyanoacrylate-lipiodol-ethanol (NLE) before liver resectiohepatocellular carcinoma,intrahepatic cholangiocarcinoma,metastatic liver tumorJPRN-UMIN000024103Wakayama medical university10