NCT01430806Unknown不适用
Dronedarone for Patients With Recurrent ICD Shocks Due to Ventricular Arrhythmia Resistant to Their Antiarrhythmic Drug Therapy or Ablation
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 入组人数
- 20
- 主要终点
- Number of ICD shocks due to VT in the 6 months period after starting Dronedarone
研究概览
简要总结
Recurrent ICD shocks are a serious problem in pts with ICD. Treatment failure with other antiarrhythmics and ablation are common. Dronedarone is a new antiarrhythmic drug with ion channel properties similar to amiodarone.
Several case reports have shown promising results with Dronedarone for this patient population.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Recurernt ICD shocks depite other antiarrhythmic drug therapy
排除标准
- •CHF NYHA IV OR DECMPENSATED III
- •PERMANENT AF
- •LIVER DYSFUNCION
- •CR CLEARANCE <30
研究组 & 干预措施
Dronedrone Arm
Other
干预措施: Dronedarone (Drug)
Dronedrone Arm
Other
干预措施: Dronedarone arm (Drug)
结局指标
主要结局
Number of ICD shocks due to VT in the 6 months period after starting Dronedarone
时间窗: 1 year
次要结局
未报告次要终点
研究者
moti haim
Director, Electrophysiology Service,
Rabin Medical Center
相似试验
终止
3 期
Catheter Ablation Versus Amiodarone for Shock Prophylaxis in Defibrillator Patients With Ventricular TachycardiaDefibrillators, ImplantableTachycardia, VentricularNCT01097330Population Health Research Institute12
终止
3 期
European Trial of Dronedarone in Moderate to Severe Congestive Heart FailureCongestive Heart FailureNCT00696631Sanofi653
进行中（未招募）
不适用
Dronedarone in pacemaker patients with paroxysmal atrial fibrillation - DROPPAFParoxysmal atrial fibrillationEUCTR2010-019442-87-GBEast Sussex NHS Trust
Unknown
4 期
Dronedarone in Pacemakers Patients With Paroxysmal Atrial FibrillationParoxysmal Atrial FibrillationNCT01070667Eastbourne General Hospital50
招募中
4 期
Effect of Prolonged Use of Dronedarone on Recurrence in Patients With Non-paroxysmal Atrial Fibrillation After Radiofrequency AblationAtrial FibrillationNCT05655468Shanghai East Hospital268