NCT01224470已完成不适用
The Effects of Intravenous Dexmedetomidine on Spinal Anesthesia Using Low Dose Diluted Bupivacaine for Transurethral Resection of Prostate
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 51
- 试验地点
- 1
研究概览
简要总结
Dexmedetomidine is a new selective and potent alpha-2 agonist. It has centrally acting anesthetic properties. It has been known that intrathecal addition of alpha-2 adrenergic agents result in prolongation of the duration of the sensory and motor blockade induced by hyperbaric bupivacaine. But the effects of intravenous dexmedetomidine on the spinal block was not evaluated. The aim of study is to assess the effect of intravenous dexmedetomidine on the low-dose spinal anesthesia for the transurethral surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 —(Adult, Older Adult)
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •ASA class I or II
- •Elective transurethral prostatectomy
- •aged > 20
排除标准
- •Coagulation deficiency
- •infection on the back
- •Congestive heart failure or arrythmia
- •Chronic alcoholic disease
- •Antidepressants therapy
研究组 & 干预措施
bupivacaine
Active Comparator
0.5% bupivacaine 1.2 mL + normal saline 0.8 mL = total 2 mL
干预措施: Dexmedetomidine (Drug)
saline
Placebo Comparator
干预措施: Dexmedetomidine (Drug)
研究者
研究点 (1)
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