Prevalence of Thyroid Dysfunction and Anti-thyroid Antibodies in Infertile Women

The study population will be divided into three groups:

• Group (A) consisting of 40 infertile women with either unexplained or anovulatory infertility with/without associated male factor of infertility,
• Group (B) consisting of 40 infertile women with tubal (mechanical) factor of infertility with/without associated male factor of infertility, and
• Group (C) consisting of 40 women with exclusive male factor of infertility and will be used as a control group.

. All women will be subjected to:

• Informed consent
• Full history taking, including age, duration of infertility and whether primary or secondary
• General and pelvix examination
• Trans-vaginal ultrasonography
• Determination of hormonal profile (FSH, LH, Estradiol, Prolactin)
• Determination of ovulatory status (by previous documented history of induction of ovulation OR previous ultrasonography OR previous estimation midluteal serum progesterone, etc ...)
• Determination of of tubal patency (by previous hysterosalpingiography or laparoscopy)
• Determination of presence of male factor (by seminal fluid analysis)
• Determination of TSH and antithyroid antibodies (antithyroglobulin and antithyroid peroxidase) blood levels