Exercise Type That Faster Reduces Postprandial Glycemia.
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 11
- 试验地点
- 2
- 主要终点
- Blood insulin concentration
研究概览
简要总结
It is well established that a bout of 50 min of continuous moderate intensity exercise, improves insulin sensitivity up to 48 hours after the bout. However, it is less well known, what is the exercise type more efficient to buffer the elevations in blood glucose elicited by carbohydrate ingestion. The purpose of this study is to elucidate if intervalic exercise is superior to continous on improving postprandial glycemic control.
详细描述
Carbohydrate oxidation, glucose and insulin blood concentrations, isotopically measured rate of appearance of endogenous and exogenous glucose will be measured in 4 ocassions.
Participants will undergo in a cross-over randomized fashion the following trials:
- Exercise pedalling during 50 min at 60% of their VO2max followed by an oral glucose tolerance test (OGTT).
- Exercise pedalling during 50 min in a hot environment (33ºC) at 60% of their VO2max followed by an oral glucose tolerance test (OGTT).
- Exercise pedalling during 50 min using intervalic bouts averaging 60% of VO2max followed by an oral glucose tolerance test (OGTT).
- No exercise, followed by an oral glucose tolerance test (OGTT).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Participant must be capable and willing to provide consent, understand, instructions and protocols.
- •Minimal fitness level to be able to complete 50 min of continous exercise at a moderate intensity.
排除标准
- •Pregnancy
- •Any non-controlled medical condition which could influence results or could be worsened by exercise
结局指标
主要结局
Blood insulin concentration
时间窗: 16 weeks
Incremental area under the curve during the 120 min of the oral glucose tolerance test
Blood glucose concentration
时间窗: 16 weeks
Incremental area under the curve during the 120 min of the oral glucose tolerance test
次要结局
- Carbohydrate oxidation(16 weeks)
- Turnover rate of endogenous and exogenous glucose(16 weeks)
研究者
Ricardo Mora
Director of the Exercise Lab at Toledo
University of Castilla-La Mancha