Evaluation of PCO2 and PO2 Values in the Pulmonary Artery and in the Superior Vena Cava: Relationship With Cardiac Output, Hematocrit and Post Operative Organ Dysfunction
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 2
- 主要终点
- PCO2 gap changes
研究概览
简要总结
The study is about comparing blood samples obtained from the superior vena cava and the pulmonary artery. The investigators will compare the values of PCO2 and PO2 from these two sites, in order to see if exists a PCO2 gap and a PO2 gap, different from zero. Moreover the investigators want to find out if these gaps are related with changes in the cardiac output, the hematocrit or if they can predict post operative dysfunctions.
Blood samples will be taken at six different times as scheduled by the protocol. Along with the two venous blood samples, an arterial blood sample will be taken too, from a radial of femoral artery catheter.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •age > 18 years
- •patient undergoing cardiac surgery with extracorporeal circulation
- •hemodynamic monitoring with a central venous catheter and a Swan Ganz catheter placed in the internal left giugulare vein
排除标准
- •severe tricuspid insufficiency
- •EF < 50%
- •SOFA score >1 in at least one of all the criteria
结局指标
主要结局
PCO2 gap changes
时间窗: two days
See if exists a PCO2 pa-svc gap different from zero in patients undergoing cardiac surgery
PO2 gap changes
时间窗: two days
See if exists a PCO2 pa-svc gap different from zero in patients undergoing cardiac surgery
次要结局
未报告次要终点
研究者
Franco Cavaliere
Professor
Catholic University of the Sacred Heart