Comparison of the antibacterial effect of tetracycline gel and gel containing mesoporous silica nanoparticles loaded with tetracycline in the gingival sulcus fluid at the site of junction between the implant and the abutment

Tabriz University of Medical Sciences0 个研究点目标入组 15 人开始时间: 待定最近更新: 2021年5月26日

适应症

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•1- Having at least 3 implants in one jaw
•2- Having a minimum age of 18 years
•3- The depth of the probe around the implant is between 1-3 mm (height of the abutment heel inside the gingiva is maximum 3 mm)
•4- Possibility of placing zirconia crown with upper gingival margin
•5- At least 4 months have passed since the extraction of the replacement teeth.

•1- Pregnant and lactating women
•2- Patients receiving antibiotics in the last 6 months
•3- Having any systemic disease such as diabetes that affects oral health
•4- Addiction to drugs, cigarettes or alcohol
•5-History of allergy to tetracycline
•6- Based on the flowchart of diagnosis of covid 19 in the levels of outpatient services for definite people with coronary heart disease and suspected of it (1. History of dry cough or chills or sore throat with shortness of breath with or without fever, which can be justified by another etiological factor 2. A patient with fever or respiratory symptoms (whatever the severity): A. Have a history of close contact with a probable / definite case of covid 19 within 14 days prior to the onset of symptoms. Health personnel)
•7- Patients with bone thickness less than 5 mm in cbct and patients need graft and bone reconstruction
•8- Presence of periodontal disease in other

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