Development and Evaluation of a Cognitive Rehabilitation Program for Persons With Multiple Sclerosis
试验速览
- 阶段
- 不适用
- 入组人数
- 50
- 试验地点
- 2
- 主要终点
- Cognitive strategy use
研究概览
简要总结
Multiple sclerosis (MS) is a progressive neurological disease that affects over 2.5 million people worldwide. Up to 50% of persons with MS (PwMS) will experience some form of cognitive impairment as a result of the disease including disturbances in memory, attention, concentration, information processing, and executive functions such as problem solving, and self-monitoring. MS-related cognitive impairments negatively affect many aspects of functioning and independent participation in everyday life. Thus, PwMS who experience cognitive impairments face a wide array of recurring barriers that pose grave challenges to carrying out everyday activities while trying to maintain multiple life roles and as they age.
Management of cognitive symptoms can be addressed through rehabilitation which has the potential to reduce disability, prevent complications of the disease, and enhance participation, independence, and quality of life. Considering the high frequency of cognitive impairments in MS and their significant, complex impact on functioning and independence, it is critical that cognitive interventions be an essential component of MS rehabilitation.
The overarching goal of this study is to develop and test a self-management, group-based cognitive rehabilitation program designed specifically for PwMS.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosis of MS
- •18 years of age or older
- •Self-report of cognitive difficulties
排除标准
- •Exacerbation of symptoms in past 3 months
- •History of TBI, CVA, epilepsy, Psychiatric condition, drug/alcohol abuse
结局指标
主要结局
Cognitive strategy use
时间窗: pre intervention, post intervention, 3,6,12 month followup
次要结局
- Cognitive self-efficacy(pre-intervention, post intervention, 3,6,12 month followup)
研究者
Eynat Shevil
Dr. Eynat Shevil
Tel Aviv University
