NCT01985932已完成不适用
A Prospective Study Evaluating Non-Endorectal Coil Functional MRI Identification of Intraprostatic Tumor During Radiation Treatment Planning
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 15
- 试验地点
- 2
- 主要终点
- Number of Participants With Adverse Events
研究概览
简要总结
This study is being done to evaluate the use of MRI during radiation treatment planning to identify areas of tumor within the prostate to aid in future treatment planning and targeting of prostate cancer. This study will be conducted at the University of Pennsylvania Health System. The study is projected to run for 18 months. Subjects will be male 18 or older with a prostate cancer diagnosis and treatment plansat the Department of Radiation Oncology.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •Age 18 or older
- •Biopsy proven prostate cancer without evidence of metastatic disease
- •Planned definitive external beam RT with daily ERB and implanted Visicoil fiducial markers.
- •Prior fMRI-ec documenting an IPL 25 mm2 in axial bidimensional diameter product, concordant with intraprostatic tumor location as documented on transrectal ultrasoundbiopsy
- •Subject capable of giving informed consent for standard external beam RT and for the study.
- •No current contraindication that would prevent MRI or gadolinium contrast.
排除标准
- •Metastatic disease
- •Lack of fMRI-ec documeneting an IPL 25 mm2 in axial bidimensional product, concordant with intraprostatic tumor location as documented on transrectal untrasound biopsy
- •Neoadjuvant androgen deprivation therapy greater than 10 weeks, defined from date of LHRH analog injection to date of fMRI-sim
- •Contraindication that would prevent MRI or gadolinium contrast
- •GFR 30 mL/min/1.73m2 per Crockoft-Gault formula.
结局指标
主要结局
Number of Participants With Adverse Events
时间窗: 2 years
次要结局
未报告次要终点
研究者
研究点 (2)
Loading locations...
相似试验
进行中（未招募）
不适用
Trial to Compare MRI-guided Precision Prone Irradiation (PPI) Versus CT-guided Breast IrradiationBreast CancerNCT05731791Weill Medical College of Cornell University17
已完成
1 期
MRI-Guided Radiation Therapy in Treating Patients Who Have Undergone Surgery to Remove the ProstateAdenocarcinoma of the ProstateStage I Prostate CancerStage II Prostate CancerStage III Prostate CancerProstate CancerNCT01028885Abramson Cancer Center at Penn Medicine10
已完成
不适用
Magnetic Resonance Imaging (MRI) in MotionLiver Cancer, Lung Cancer, Pancreatic CancerNCT02019199Duke University25
招募中
不适用
Post-operative Radiotherapy Omission in Selected Patients With Early Breast Cancer Trial International VErsion (PROSPECTIVE)Breast Cancer FemaleBreast CancerNCT06445738Breast Cancer Trials, Australia and New Zealand1,400
已完成
不适用
Study Evaluating the Use of MRI on CMS PatientsPacemakerImplantable Cardioverter DefibrillatorsNCT02513056University of Pennsylvania872