Articaine and Dexmedetomidine - Supplemented Articaine for Arteriovenous Fistula Creation Under Ultrasound- Guided Supraclavicular Block
试验速览
- 阶段
- 早期 1 期
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Duration of sensory block
研究概览
简要总结
The aim of this study to test efficacy of adding dexmedetomidine to articaine on sensory, motor and duration of analgesia during hemodialysis fistula creation under ultrasound guided supraclavicular block
详细描述
Adult fifty patient with chronic renal failure on hemodialysis, scheduled for arteriovenous fistula creation under ultrasound guided supraclavicular block. Patients were randomly allocated in two group. The articaine group (group A) received 40 ml articaine hydrochloride 2% and articaine-dexmedetomidine group (group AD) received 40 ml. Of articaine 2% mixed with dexmedetomidine (1micogram/kg)
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Care Provider, Investigator)
入排标准
- 年龄范围
- 25 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •adult patient with chronic renal failure on hemodialysis scheduled for radiocephalic fistula creation
排除标准
- •Allergy to local anesthetics.
- •Infection at the site of needle insertion.
- •Those having international normalized ratio more than 1.
- •Coagulopathy.
- •Neuromuscular, or severe hepatic or severe pulmonary disease.
- •Those having epilepsy.
- •Patients who refused to participate.
研究组 & 干预措施
Group A
Patients received ultrasound guided supraclavicular block with 40 ml of Articaine hydrochloride 2%
干预措施: Articaine (Drug)
Group AD
Patients received ultrasound guided supraclavicular block with 40 ml articaine 2% mixed with dexmedetomidine (1 µg/kg).
干预措施: Articaine (Drug)
Group AD
Patients received ultrasound guided supraclavicular block with 40 ml articaine 2% mixed with dexmedetomidine (1 µg/kg).
干预措施: Dexmedetomidine (Drug)
结局指标
主要结局
Duration of sensory block
时间窗: 24 hours
Sensory block time tested by pinprick test measured in minute
Duration of motor block
时间窗: 24 hours
Motor block time tested by Bromage scale measured in minutes
次要结局
- Duration of analgesia(24 hours)
研究者
simon Halim Armanious
Simon Halim, MD S. Armanious
Ain Shams University