Behavioral Rigidity as a Transdiagnostic Dynamic Process in Patients With Substance Use Disorders: A Longitudinal Observational Study
试验速览
- 阶段
- 不适用
- 状态
- Enrolling By Invitation
- 发起方
- 入组人数
- 35
- 试验地点
- 1
- 主要终点
- Change in negative automatic thoughts measured by the Automatic Thoughts Questionnaire 8-item version
研究概览
简要总结
Behavioral rigidity, the tendency to maintain inflexible patterns of thinking and acting despite changing circumstances, is a common feature in substance use disorders, depression, and anxiety. This observational study aims to measure behavioral rigidity as a dynamic, transdiagnostic process in patients undergoing residential treatment for substance use. Using a longitudinal intensive repeated-measures design, participants complete weekly assessments of cognitive reactivity (Automatic Thoughts Questionnaire-8 item version, ATQ-8), behavioral activation (Behavioral Activation for Depression Scale, BADS), and experiential avoidance. A Behavioral Rigidity Index (BRI) is derived from these measures. Additionally, natural language processing (NLP) is applied to therapy session transcripts to quantify linguistic absolutism (e.g., use of words like "always," "never") and affective polarity. Bayesian multilevel models examine whether rigidity predicts current and next-week clinical status. The study also explores whether linguistic markers add unique predictive value beyond self-reports. Results may inform personalized monitoring and interventions targeting psychological inflexibility in addiction treatment.
详细描述
This is an observational, longitudinal intensive study with repeated measures (weekly assessments) conducted in a residential therapeutic community in Mexico. Participants are adults (N=34, age 18-60) with substance use disorder and co-occurring emotional dysregulation or behavioral maladaptation, receiving standard psychosocial treatment (not assigned by the research protocol). Inclusion requires a minimum stay of four weeks, at least three complete measurement time points, and ability to complete self-reports. Exclusion criteria: severe neurocognitive impairment, acute psychotic symptoms, or incomplete longitudinal records.
Measures are collected at the beginning of each weekly therapy session:
Automatic Thoughts Questionnaire-8 (ATQ-8): frequency of negative automatic thoughts (higher scores indicate more frequent negative automatic thoughts).
Behavioral Activation for Depression Scale (BADS): subscales of Activation (goal-directed activity) and Avoidance/Rumination (experiential avoidance).
From these, a Behavioral Rigidity Index (BRI) is computed in two versions:
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Minimum stay of four weeks in the residential treatment program
- •At least three complete longitudinal measurement time points
- •Ability to read, understand, and respond to self-report instruments in Spanish
- •Capacity to participate in structured clinical sessions
- •Diagnosis of substance use disorder (clinical assessment)
排除标准
- •Severe neurocognitive impairment
- •Acute psychotic symptoms
- •Incomplete longitudinal records (less than three time points)
- •Inability to complete self-report measures due to cognitive or language barriers
研究组 & 干预措施
Participants with Substance Use Disorder
Adult patients (n=34) receiving standard residential treatment for substance use disorder in a therapeutic community. All participants undergo weekly assessments of cognitive reactivity (Automatic Thoughts Questionnaire-8 item version, ATQ-8), behavioral activation (Behavioral Activation for Depression Scale, BADS), and natural language processing (NLP) of therapy session transcripts.
干预措施: No intervention (Other)
结局指标
主要结局
Change in negative automatic thoughts measured by the Automatic Thoughts Questionnaire 8-item version
时间窗: Weekly from baseline until discharge from treatment (up to 12 weeks)
The Automatic Thoughts Questionnaire 8-item version is a self-report measure assessing the frequency of negative automatic thoughts. Total scores range from 8 to 40, with higher scores indicating more frequent negative automatic thoughts. Longitudinal change in total score across treatment is evaluated as the primary outcome.
次要结局
- Behavioral Rigidity Index - Pondered (study-derived composite index)(Weekly from baseline until discharge (up to 12 weeks))
- Behavioral activation measured by the Behavioral Activation for Depression Scale Activation subscale(Weekly from baseline until discharge (up to 12 weeks))
- Avoidance and rumination measured by the Behavioral Activation for Depression Scale Avoidance/Rumination subscale(Weekly from baseline until discharge (up to 12 weeks))
- Linguistic Rigidity Index derived from therapy session transcripts(Weekly from baseline until discharge (up to 12 weeks))
- Change in anxiety symptoms measured by the Generalized Anxiety Disorder 7-item scale(Weekly from baseline until discharge (up to 12 weeks))
研究者
Lauro Gutiérrez Castro
Principal Investigator
Under The Tree Therapeutic Community