2024-518949-14-00招募中2 期
Beta-blockade with landiolol in out-of-hospital cardiac arrest: a randomized, double-blind, placebo-controlled, pilot trial
适应症
相关药物
试验速览
- 阶段
- 2 期
- 状态
- 招募中
- 入组人数
- 48
- 试验地点
- 1
- 主要终点
- Time (in minutes) to sustained return of spontaneous circulation
研究概览
简要总结
To demonstrate that add-on treatment with landiolol in patients with cardiac arrest significantly decreases the time to sustained ROSC (sROSC) (time from infusion of study medication to sustained ROSC)
入排标准
- 年龄范围
- 18 years 至 65+ years（18-64 Years, 65+ Years）
- 接受健康志愿者
- 否
入选标准
- •OHCA , ³ 18 years of age • 3 or more shockable rhythms (VF or pVT) and last rhythm shockable
排除标准
- •Age > 85a • Severe head trauma or acute active bleeding • Known allergy or insensitivity to landiolol or another b-blocker
结局指标
主要结局
Time (in minutes) to sustained return of spontaneous circulation
Time (in minutes) to sustained return of spontaneous circulation
次要结局
- cummulative ROSC, temporary ROSC, sustained ROSC, survival at 24h, favorable neurologic outcome
研究者
Department of Clinical Pharmacology
Scientific
Medical University Of Vienna
研究点 (1)
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