跳至主要内容
临床试验/NCT04494152
NCT04494152Unknown不适用

Reliability of Echocardiographic Assessment of Cardiac Dimensions and Function From Subcostal View

Emergency Medical Service of the Central Bohemian Region, Czech Republic1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2020年8月20日最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
100
试验地点
1
主要终点
Reliability of left ventricular subcostal fractional shortening and left ventricular modified subcostal fractional shortening in determining the global left ventricular systolic function in critically ill patients.

研究概览

简要总结

The purpose of this study is to assess reliability of echocardiographic assessment of ventricular dimensions and function from subcostal view.

详细描述

Assessment of the function and dimensions of the right and left ventricles is a key part of Point-of-Care ultrasound in critically ill patients. According to the recent guidelines, this evaluation is performed from apical and parasternal views. However, these views may not be clearly visible in the clinical setting of critical illness and subcostal view is often preferred for its higher feasibility. Before clinical adoption, it is necessary to assess whether the isolated examination from subcostal view is reliable enough in the detection of the impairment of systolic function and the size of both ventricles and the investigators decided to evaluate this issue.

Transverse and longitudinal dimensions and function of both ventricles will be measured calculated by transthoracic echocardiography in critically ill patients in the intensive care unit from parasternal and apical views following the recent guidelines. Systolic function of the left ventricle will be expressed by the left ventricular ejection fraction (calculated by biplane method of disc summation) and by the fraction shortening. Systolic function of the right ventricle will be assessed by the tricuspid annular plane systolic excursion, fractional area change, tricuspid lateral annular systolic velocity, and right ventricular index of myocardial performance. From subcostal view, transverse dimensions of both ventricles and novel parameters of systolic function (subcostal tricuspid annular plane systolic excursion, right ventricular subcostal fraction shortening, right ventricular modified subcostal fraction shortening, left ventricular subcostal fraction shortening and left ventricular modified fraction shortening) will be measured.

Then, the reliability of parameters measured in subcostal view will be tested by comparison with conventional parameters taken from apical and parasternal view by correlation analysis and diagnostic test evaluation. The most reliable thresholds of parameters from subcostal view will be calculated by receiver operating characteristic analysis.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Inpatients
  • All patients hospitalised in intensive care unit indicated for transthoracic echocardiography examination

排除标准

  • Age <18 years
  • Insufficient imaging quality of transthoracic echocardiography
  • Refusal of echocardiographic examination by patient

结局指标

主要结局

Reliability of left ventricular subcostal fractional shortening and left ventricular modified subcostal fractional shortening in determining the global left ventricular systolic function in critically ill patients.

时间窗: During the procedure

Left ventricular subcostal fractional shortening and left ventricular modified subcostal fractional shortening are new potential echocardiographic parameters of left ventricular systolic function measurable from subcostal view.

Reliability of right ventricular subcostal fractional shortening and right ventricular modified subcostal fractional shortening in determining the global right ventricular systolic function in critically ill patients.

时间窗: During the procedure

Right ventricular subcostal fractional shortening and right ventricular modified subcostal fractional shortening are new potential echocardiographic parameters of right ventricular systolic function measurable from subcostal view.

次要结局

  • Reliability of echocardiographic parameters evaluating the size of the right ventricle measured in a subcostal view in critically ill patients.(During the procedure)
  • Reliability of echocardiographic parameters evaluating the structure of the left ventricle measured in a subcostal view in critically ill patients.(During the procedure)

研究者

发起方
Emergency Medical Service of the Central Bohemian Region, Czech Republic
申办方类型
Other
责任方
Principal Investigator
主要研究者

Roman Skulec

Principal investigator

Emergency Medical Service of the Central Bohemian Region, Czech Republic

研究点 (1)

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