Incremental Value of Musculoskeletal Ultrasound After DETAIL and IBIS-Q Screening for Early Detection of IBD-associated Spondyloarthritis.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Prevalence of undiagnosed spondyloarthritis
研究概览
简要总结
This study aims to evaluate the screening performance of the DETAIL and IBIS-Q questionnaires followed by musculoskeletal ultrasound (MSUS) for the early detection of spondyloarthritis in patients previously diagnosed with Inflammatory Bowel Disease (IBD).
详细描述
Inflammatory bowel disease (IBD) is frequently associated with extraintestinal manifestations, with spondyloarthritis (SpA) being the most common. Early detection is crucial to prevent structural damage. This prospective study will screen consecutive adult patients with IBD using the DETAIL and IBIS-Q questionnaires. Patients will then undergo a comprehensive clinical and musculoskeletal ultrasound (MSUS) assessment to evaluate the incremental diagnostic value of ultrasound in detecting early and subclinical SpA.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult Aged 18 years old or more Confirmed diagnosis of IBD (by established clinical, endoscopic, and histopathological criteria).
- •Patient provides informed written consent to participate
排除标准
- •Known, pre-existing diagnosis of Spondyloarthritis or any other concomitant systemic autoimmune rheumatic disease.
- •Severe secondary osteoarthritis or major joint trauma/surgery mimicking SpA. Cognitive impairment or communication barriers preventing comprehension or completion of questionnaires
结局指标
主要结局
Prevalence of undiagnosed spondyloarthritis
时间窗: At the time of clinical evaluation (up to 12 months)
The percentage of patients with inflammatory bowel disease (IBD) who are newly diagnosed with spondyloarthritis based on DETAIL and IBIS-Q questionnaires followed by musculoskeletal ultrasound (MSUS).
次要结局
未报告次要终点
研究者
Shaimaa Salah Abdelaziz Sayed
Internal Medicine Resident
Assiut University