Dexamethasone vs methylprednisolone high dose for COVID-19 pneumonia

Clínica Medellín - Grupo Quirónsalud0 个研究点目标入组 213 人开始时间: 2020年11月27日最近更新: 2024年1月15日

试验速览

2021 Results article in https://pubmed.ncbi.nlm.nih.gov/34033648/ (added 14/03/2022)

•1. Over 18 years of age
•2. Hospitalized with COVID-19 pneumonia confirmed by positive Real-Time Reverse Transcription Polymerase Chain Reaction for SARS-CoV2 (RT-PCR SARS-CoV-2) by Berlin protocol
•3. Radiological confirmation of pneumonia

•1. Contraindications associated with corticosteroids
•2. Dissent for medical management
•3. Death in the first 24 hours
•4. Patient in palliative care or with a life expectancy of fewer than 6 months
•5. If the patient required admission to the ICU and did not receive at least two doses of the corticosteroid
•6. If the patient receives at least two doses of methylprednisolone but did not continue with prednisone, they were not included, but their outcome continued to be monitored
•7. Patients who also received less than 2 days of dexamethasone treatment were withdrawn from study follow-up

发起方

Clínica Medellín - Grupo Quirónsalud