NCT05426408招募中不适用
Stockholm Myocardial Infarction with Nonobstructive Coronaries Study 3 - Pilot Study of Prevalence of Coronary Microvascular Dysfunction in Myocardial Infarction with Nonobstructive Coronary Arteries
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 85
- 试验地点
- 2
- 主要终点
- Diagnostic yield
研究概览
简要总结
The present pilot study will investigate the prevalence of CMD in an unselected cohort of patients with the working diagnosis MINOCA and to study if the diagnostic yield can be improved by adding adenosine to the CMR investigation. Patient will be their own controls.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
盲法说明
The investigators who will perform the evaluation of the CMR investigations will be blinded to all clinical data.
入排标准
- 年龄范围
- 35 Years 至 79 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •a suspected diagnosis of MINOCA or takotsubo syndrome with coronary angiography without diameter stenosis ≥50%
- •age 35-80 years
- •reading and writing proficiency in Swedish
排除标准
- •Claustrofobia
- •Arrythmia and/or pacemaker (atrial fibrillation and AV-block I- III)
- •Asthma or severe chronic obstructive lung disease
- •eGFR < 30 ml/min
- •spontaneous coronary artery dissection
- •acute pulmonary embolism
- •acute myocardial infarction type 2
- •cardiomyopathy other than takotsubo syndrome
- •a previous myocardial infarction due to CAD
结局指标
主要结局
Diagnostic yield
时间窗: Through investigation completion, usually 2 hours
To increase the diagnostic yield of CMR imaging in MINOCA as a working diagnosis
次要结局
- Prevalence of CMD in different final MINOCA diagnoses(Through investigation completion, usually 2 hours)
- Prevalence of CMD in MINOCA(Through investigation completion, usually 2 hours)
- Angina pectoris(3 Months)
研究者
Per Tornvall
Professor
Karolinska Institutet
研究点 (2)
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