COMPARING THE EFFICACY OF 0.2 PERCENT HYALURONIC ACID GEL AND OZONATED OIL IN WOUND HEALING AFTER LASER-ASSISTED DEPIGMENTATION
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 25
- 试验地点
- 1
- 主要终点
- wound healing, visual analog scale.
研究概览
简要总结
The current randomized split-mouth study consists of 25 systematically healthy patients. Patients will be chosen according to specified inclusion and exclusion criteria. Informed consent will be acquired from each patient, and subsequently, they are randomly assigned to one of two groups. Group I patients will receive laser depigmentation with 0.2 percent hyaluronic acid gel and group 2 will receive laser assisted depigmentation with ozonated oil.Initially scaling and root planning will be done followed by oral hygiene instructions. patients will be re evaluated after 1 week for optimum oral hygiene.Depigmentation will be performed using diode laser(800nm, 1W) under topical anesthesia, required amount of 0.2 percent hyaluronic acid gel and ozonated oil will be applied at de-epithelized area followed by periodontal dressing placement.The patients were recalled on the 3rd day and the periodontal pack was removed.
- Pain was assessed using VAS score on days 3 & 7 day.
- Healing was assessed using Landry, Turnbull, and Howley wound healing index on days 3 & 7day.
- Pigmentation was assessed using Dummett Oral Pigmentation Index (DOPI), at Baseline & after 3 months.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 20.00 Year(s) 至 55.00 Year(s)（—）
- 性别
- All
入选标准
- •1 Patients aged between 20-55 years.
- •2 Systemically healthy patients.
- •3 Patients who met Dummet Pigementation index of score 2 and 3.
排除标准
- •1 Patients on antibiotics or anti-inflammatory medicines.
- •2 History of periodontal surgery within the last 6 months.
- •3 Women who are pregnant and lactating mothers.
- •4 Patients with adverse habits.
结局指标
主要结局
wound healing, visual analog scale.
时间窗: day 3 and 7.
次要结局
- pigmentation(baseline and 3 months)
研究者
Dr Fathima suharal
SREE SAI DENTAL COLLEGE AND RESEARCH INSTITUTE