NCT01572402已完成不适用
Postprandial Insulin Secretion, Oxidative Stress and Gastrointestinal Peptides in Patients With Type 2 Diabetes Versus Healthy Subjects
Institute for Clinical and Experimental Medicine2 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2012年1月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 100
- 试验地点
- 2
- 主要终点
- Postprandial oxidative stress
研究概览
简要总结
Insulin secretion, plasma lipids, oxidative stress markers and gastrointestinal peptides will be measured in patients with type 2 diabetes versus healthy subjects in a fasting status and in response to standard meals (at times 0', 30', 60', 120' and 180').
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 30 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •40 individuals with type 2 diabetes treated by diet only or oral hypogylycemic agents,
- •diabetes duration at least 1 year,
- •both men and women,
- •age 30-65 years,
- •BMI 27-50 kg/m². The subjects will be explained aims, methods and risks of the study and they will sign informed consent
排除标准
- •gravidity,
- •lactation,
- •drug abuse,
- •insulin therapy
结局指标
主要结局
Postprandial oxidative stress
时间窗: up to 2 months
Postprandial plasma concentrations of gastrointestinal peptides
时间窗: up to 2 months
次要结局
- Postprandial insulin secretion - relationship to oxidative stress and gastrointestinal peptides(up to 2 months)
- Postprandial plasma lipids(up to 2 months)
研究者
Hana Kahleova
Principal Investigator
Institute for Clinical and Experimental Medicine
研究点 (2)
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