ACTRN12610000652077已完成3 期
In adolescents with Attention Deficit Hyperactivity Disorder (ADHD), how does methylphenidate compared to placebo, effect Blood Oxygenation Level Dependent (BOLD) response as measured by functional Magnetic Resonance Imaging (fMRI), and how does the response vary with difference in the dopamine transporter (DAT1) gene.
Dr. Tim Silk0 个研究点目标入组 36 人开始时间: 2010年8月11日最近更新:
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 发起方
- 入组人数
- 36
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 8 Years 至 18 Years（—）
- 性别
- All
入选标准
- •ADHD (combined type)
- •Healthy, matched control adolescents (Placebo only)
- •right handed
排除标准
- •Weight under 35kg
- •Full scale Intelligence Quotient (FSIQ) >70
- •Conners Parent Rating Scale (CPRS) >65 for ADHD, <60 for controls
- •gluten intolerance (due to presence in placebo)
- •wearing dental braces
- •no reading disabilities,
- •no comorbidities, of major depression, Autism Spectrum Disorders, or psychosis
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