Randomized phase II trial of gemcitabine(GEM) and carboplatin (CBDCA) with or without Dexamethasone(Dex) in untreated non-small cell lung cancer (NSCLC). - Randomized phase II trial of dexmethasone as premedication to GEM and CBDCA

Kyoto Thoracic Oncology Research Group (KTORG)0 个研究点目标入组 76 人开始时间: 2007年1月1日最近更新: 2023年10月17日

适应症

试验速览

暂无简介。

•1)Clinically apparent interstitial pneumonia in chest X ray or CT 2)Pleural or pericardial effusion, or ascites requiring treatment 3)Treated Pericardial effusion or ascites 4)SVC syndrome 5)Brain metastasis requiring treatment 6)Patients with active concomitant cancer 7)Uncontrolled diabetes 8)Severe cardiovascular diseases a.uncontrollable hypertension b.congestive heart failure c.unstable angina, myocardial infarction or PTCA/CAGB therapy within the past six months d.uncontrollable arrythmias 9) Patients with liver cirrhosis 10) Pregnant or lactation women, or women with known or suspected pregnancy and men who want let to pregnancy 11) Medical history of serious allergic reactions to any drug 12)Active inflammatory diseases 13)Active or chronic infectious diseases (especially patients with positive HBs-Ag or active mycobacterial infection) 14) Regular use of steroids or immunosupressive drugs 15)Refusal to blood transfusion 16)Patient with known bleeding disorders 17) Inappropriate patients for this study judged by the physicians.

发起方

Kyoto Thoracic Oncology Research Group (KTORG)