DRKS00004928已完成未知
Temporal percpeption of patients suffering from Essential Tremor with and without Deep Brain Stimulation - ColTrem V.2
Klinik und Poliklinik für NeurologieUniversitätsklinik zu Köln0 个研究点目标入组 48 人开始时间: 2013年6月3日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 48
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Non-randomized controlled study
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 80 Years（—）
- 性别
- All
入选标准
- •Age- and sex-matched control probands:
- •Age between 18-80 years
- •ET-patients without Deep Brain Stimulation:
- •Patients with essential tremor (ET) fulfilling the criteria of the consensus statement of the Movement Disorder Society
- •Age between 18-80 years
- •Disease duration of at least 5 years
- •ET-patienten with Deep Brain Stimulation:
- •Patients with essential tremor (ET) fulfilling the criteria of the consensus statement of the Movement Disorder Society and DBS for at least 3 months
- •Age between 18-80 years
- •Disease duration of at least 5 years
- •Electrode localisation in the ventrolateral thalamus or areas just below (posterior subthalamic area, PSA)
- •Tolerabel tremor after switching off the stimulation
排除标准
- •Age- and sex-matched controls:
- •Subjects with a severe neurologic disease (e.g. epilepsy, brain tumor, ischaemic stroke, dystonia)
- •Conspicuities in the MRI
- •Medication affecting cognition which cannot be withdrawn for at least 24 hours
- •Hypokinesia or resting tremor possibly indicating an underlying Parkinson's disease
- •DemTect < 9
- •Severe depression
- •ET-patients without Deep Brain Stimulation:
- •Patients with a severe neurologic disease other than essential tremor (e.g. epilepsy, brain tumor, ischaemic stroke, dystonia)
- •Conspicuities in the MRI
- •Medication affecting cognition which cannot be withdrawn for at least 24 hours
- •Hypokinesia or resting tremor possibly indicating an underlying Parkinson's disease
- •DemTect < 9
- •Severe depression
- •ET-patients with Deep Brain Stimulation:
- •Patients with a severe neurologic disease other than essential tremor (e.g. epilepsy, brain tumor, ischaemic stroke, dystonia)
- •Medication affecting cognition which cannot be withdrawn for at least 24 hours
- •Hypokinesia or resting tremor possibly indicating an underlying Parkinson's disease
- •DemTect < 9
- •Severe depression
研究者
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