Non-invasive Evaluation of Lymphoma Patients Based on Artificial Intelligence and PET/MRI
试验速览
- 阶段
- 不适用
- 入组人数
- 100
- 主要终点
- Patients that preform 18F-FDG PET/MRI and the routinely PET/CT
研究概览
简要总结
18F-FDG PET/MR imaging protocol integrating advanced MR vascular imaging sequences, along with computerized quantitative methods for data analysis, is expected to serve as an objective tool for assessment of lymphoma patients. The aim of this prospective study is to develop an automatic artificial intelligence-based tool for the assessment of early response to treatment and evaluation of residual masses in patients with lymphoma. Specific objectives are:
- To evaluate the added value of 18F-FDG PET/MRI compared with PET/CT in imaging lymphoma.
- To optimize PET/MR imaging protocol for lymphoma assessment.
- To develop an automated tool for staging patients with lymphoma.
- To develop an automated method for early prediction of response to therapy and prognosis in patients with lymphoma.
- To develop an automated non-invasive tool for discriminating benign from active residual masses at end of treatment in patients with lymphoma.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 120 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients with newly diagnosed hodgkin's, aggressive non-hodgkin's and follicular lymphoma (for whom the PET/CT is the imaging modality of choice)/
- •Patients aged 18 years or older of both sexes.
- •Patients treated at Tel-Aviv Sourasky Medical center.
排除标准
- •contraindication to MRI or to intravenous gadolinium injection.
结局指标
主要结局
Patients that preform 18F-FDG PET/MRI and the routinely PET/CT
时间窗: 1 year
Patients that preform 18F-FDG PET/MRI and the routinely PET/CT, and the investigators optimize PET/MRI imaging protocol, and to develop an automated artificial intelligence-based tool for assessment of early response to treatment in patients with lymphoma.
次要结局
未报告次要终点