NCT00296114已完成不适用
Pancreatic Cancer Serum and DNA Repository
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 690
- 试验地点
- 10
研究概览
简要总结
To prospectively collect serum and DNA samples from subjects with pancreatic cancer, pancreatitis, liver disease, and from healthy and at-risk volunteers in order to identify novel biomarkers for early diagnosis, differential diagnosis, stage, natural history of the disease, response to treatment, and to identify novel targets for therapeutic interventions. In particular:
详细描述
- To establish a central pancreatic cancer specimen repository to serve as a resource for current and future scientific studies.
- To utilize the PCRT clinical data base to perform clinicopathologic correlation with the results of those studies.
- To test new hypotheses as they emerge.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Ages Eligible for Study: 18 Years and above, Genders Eligible for Study: Both
- •Inclusion Criteria:
- •4.1 At the time of subject registration, CRAB will verify the institution's IRB date to ensure that the subject can be enrolled.
- •4.2 Potential study participants must meet the eligibility criteria found in Section 12.0 (Eligibility Checklist). Candidates will fall into one of four groups:
- •Pancreatic cancer patients;
- •Pancreatic and Liver Disease patients;
- •Healthy, At-Risk Volunteers (smoker, (defined as individuals who have smoked >= 100 cigarettes in their lifetime, and who currently smoke every day or some days [MMWR November 12, 2004, 53(44);1035-1037]), diabetic, and/or family history); and
- •Healthy Volunteers (no history of cancer). The Eligibility Checklist must be photocopied, completed and stored on site. Eligibility is confirmed during registration, by answering yes to the question, Have all eligibility criteria been met? on the Registration Form.
- •Eligibility Checklist:
- •Pancreatic Cancer Patient Criteria All subjects, regardless of gender and ethnicity are eligible for this study Pathological diagnosis of pancreatic malignant neoplasm Expected availability of clinical follow up data Eighteen years old or older All subjects must be informed of the investigational nature of this protocol Written, informed consent obtained in accordance with institutional and federal guidelines
- •Pancreatitis and Liver Disease Subject Criteria All subjects, regardless of gender and ethnicity are eligible for this study Pathological diagnosis of pancreatitis or liver disease Eighteen years old or older All subjects must be informed of the investigational nature of this protocol Written, informed consent obtained in accordance with institutional and federal guidelines
- •Healthy, At-Risk Volunteers All subjects, regardless of gender and ethnicity are eligible for this study Is a smoker, is diabetic AND/OR has a family history of pancreatic cancer Eighteen years old or older with no history of cancer All subjects must be informed of the investigational nature of this protocol Written, informed consent obtained in accordance with institutional and federal guidelines
- •Healthy Volunteers (no at-risk factors) All subjects, regardless of gender and ethnicity are eligible for this study Eighteen years old or older with no history of cancer All subjects must be informed of the investigational nature of this protocol Written, informed consent obtained in accordance with institutional and federal guidelines
排除标准
- 未提供
研究者
研究点 (10)
Loading locations...
相似试验
已完成
不适用
Pancreatic and Gastrointestinal Tumor Registry and Tissue CollectionPancreatic CancerNCT00584363University of Alabama at Birmingham731
招募中
不适用
Collecting Medical Information and Tissue Samples From Patients With Pancreatic Cancer or Other Pancreatic DisordersPancreatic CancerAcute PancreatitisChronic PancreatitisNCT00830557Mayo Clinic20,000
已完成
不适用
Collecting and Storing Samples of Blood From Patients With Pancreatic Cancer and Healthy ParticipantsPancreatic CancerNCT00898482Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins88
Enrolling By Invitation
不适用
Protocol to Permit the Acquisition of Circulating Tumor Material in Pancreatic DiseasesPancreatic DiseasesNCT02471170Abramson Cancer Center at Penn Medicine100
招募中
不适用
Gastrointestinal Microflora and Serum Metabolomics in Patients With Pancreatic Cancer and Chronic PancreatitisPancreatic CancerChronic PancreatitisNCT06411470Changhai Hospital600