NCT04238936已完成不适用
Levels of New Inflammatory Markers in GDM Patients; Serum Amyloid A and Interleukin-1 (IL-1) Receptor Antagonist
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Serum amyloid A
研究概览
简要总结
Serum amyloid A and Interleukin-1 (IL-1) receptor antagonist (A-SAA and IL-1Ra) values;
- Comparison of pregnant women with and without GDM diagnosis
- Comparison of insulin therapy and diet-regulated GDM patients
- Comparison of pregnant women with and without LGA (large gestational age)
- Comparison of pregnant women with and without polyhydroamnios
- Investigation of its effect on pregnancy prognosis
- In the prediction of GDM diagnosis, it is aimed to study the sensitivity and specificity of both parameters and cut off values.
(In GDM patients, liver and kidney function parameters will also be evaluated with A-SAA and IL-1Ra levels).
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 42 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Patients with 50 gr OGTT + 100 gr OGTT + at 24-28 weeks of gestation
- •Patients with 75 gr OGTT + at 24-28 weeks of gestation
- •18-42 years pregnant women
排除标准
- •any infection
- •Any known fetal chromosomal or structural anomaly
- •Preterm membrane rupture
- •Preterm delivery
- •Preeclampsia or eclampsia
- •Placenta previa
结局指标
主要结局
Serum amyloid A
时间窗: 1 week
Its level will be checked in the study group consisting of pregnant women with GDM and in the control group consisting of healthy pregnant women.
Interleukin-1 (IL-1) receptor antagonist
时间窗: 1 week
Its level will be checked in the study group consisting of pregnant women with GDM and in the control group consisting of healthy pregnant women.
次要结局
未报告次要终点
研究者
Pınar Kadirogulları
principal investigator, Pınar kadirogullari, M.D, Department of Obstetrics and Gynecology
Kanuni Sultan Suleyman Training and Research Hospital
研究点 (1)
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