The Association Between Chlorhexidine Bathing Every Other Day and Central Line-Associated Infections in Medical Intensive Care Units: An Observational Cohort Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 6,930
- 试验地点
- 1
- 主要终点
- central line-associated bloodstream infections
研究概览
简要总结
We conducted a retrospective observational cohort study assessing the relationship between regular bathing using 2% CHG wipes every other day and the occurrence of central line-associated infections (CLABSI) in patients within the medical intensive care unit (MICU).
详细描述
This study defined the post-intervention period as July 1, 2017, to June 30, 2022. During this period, one of the three medical intensive care units (MICUs) in NTUH implemented chlorhexidine gluconate (CHG) bathing as part of their daily care routine (CHG group). This decision was made in response to a higher incidence rate of vancomycin-resistant Enterococcus (VRE) bacteremia observed in that particular MICU during the preceding six months (pre-intervention period: January 1, 2017, to June 30, 2017), compared to the other two MICUs. The remaining two MICUs continued to provide usual care, which involved bathing patients with towels soaked in water and soap on a daily basis.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •all patients who were admitted to the MICU between January 2017 and June 2022
排除标准
- •patients aged under 18 years old
结局指标
主要结局
central line-associated bloodstream infections
时间窗: Will be surveyed retrospectively through the study period (January 2017 to June 2022)
the incidence rate of intensive care unit acquired central line-associated bloodstream infections
multidrug-resistant organisms bacteremia
时间窗: Will be surveyed retrospectively through the study period (January 2017 to June 2022)
the incidence of CLABSIs with blood cultures positive for multidrug-resistant organisms
次要结局
- ICU length of stay(Will be surveyed retrospectively through the study period (January 2017 to June 2022))
- ICU mortality(Will be surveyed retrospectively through the study period (January 2017 to June 2022))
- hospital length of stay(Will be surveyed retrospectively through the study period (January 2017 to June 2022))
- hospital mortality(Will be surveyed retrospectively through the study period (January 2017 to June 2022))