Clinical Evaluation of Varuni Tailam with DashmoolKwath and Varuni Tailam Nasya in the Management of kamanvata with special reference to Parkinsons Disease
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Improvement in Tremors, Rigidity and Bradykinesia
研究概览
简要总结
This study is a randomized, double blind, parallel group trial to evaluate clinical efficacy of Varuni Tailam with Dashmool Kwath and Varuni tailam nasya in the the patients of Kampvata with special reference to Parkinson’s disease. It will have two groups (30 patients in each group) with Group 1 – Varuni Tailam 10 ml with Dashmool Kwath 20ml and Varuni Tailam Nasya (2drops/nostril), Group 2 – Tablet Ldopa 100mg daily, duration will be 8 weeks. Primary outcome being improvement in Unified Parkinson’s Disease Rating Scale (UPDRS) and secondary outcome - Improvement in Ayurveda Symptoms grading of (*Kampa /*Tremor, *Stambha /*Rigidity and Asamyakgati /Bradykinesia) as per WHO scoring of Ayurveda Symptoms, IPGTRA, Jamnagar, 2011 Guidelines.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Double
入排标准
- 年龄范围
- 50.00 Year(s) 至 80.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients willing to participate and provide written consent.
- •Patients exhibiting the features of Kampavatas Age 50 to 80 yr of either sex Both freshly detected and already diagnosed cases.
排除标准
- •Patients with systemic disorders and with other complication.
- •History of repeated strokes with stepwise progression of Parkinson’s disease.
- •History of head injury.
- •History of definite encephalitis and early severe dementia.
结局指标
主要结局
Improvement in Tremors, Rigidity and Bradykinesia
时间窗: 8 Weeks
次要结局
- Improvement in Symptoms Grading((As per WHO scoring of Ayurveda Symptoms, IPGTRA, Jamnagar, 2011 guidelines) of Kampa (Tremor), Stambha (Rigidity) and Asamyakgati (Bradykinesia/Impaired mobility).)
研究者
Dr Sanandan Thapliyal
Shivalik Institute of Ayurveda and Research Dehradun